Experiences & Outcomes

• Our 95 yo lady received 200 cc weekly for three weeks. She cancelled her last IV because she felt so good. She was in a wheelchair, but once she arrived, she jumped out of her chair and walked briskly into the treatment room. 

• She said she didn’t need her eye glasses any longer. She said people could not believe her so she had to keep repeating to them that she DID NOT need her glasses. 

• She looked very spry and energetic which was much different when she initially started her yFFP infusions. 

Medical History: Overall healthy; on hormone replacement therapy (HRT); longstanding Raynaud’s phenomenon and joint pain from years of intensive weightlifting

Treatment:

​3L Young Plasma Exchange (YPE)

Outcomes:

• Experienced a surge of energy within weeks of treatment

• Reported glowing, youthful skin — notably commented on by her partner

• Raynaud’s symptoms completely resolved, even in cold environments

• Significant improvement in joint pain, allowing her to train more comfortably

• Noted enhancement in memory and mental clarity, particularly recall and processing speed

• At 60 years old, I underwent a 3-month series of young plasma infusions—1 liter each month—motivated by emerging science on regenerative signaling, mitochondrial support, and age-related resilience. What followed wasn’t just subjective vitality—it was measurable transformation. I won my age group in the Spartan Beast, a grueling endurance event that pushes both mind and muscle to their limits. My recovery improved. My focus sharpened. My energy felt steadier, more youthful.

• But perhaps most telling of all: I took 30 minutes off my marathon time and just qualified for the Boston Marathon. That kind of progress isn’t typical at any age, much less after 60. I didn’t change my diet, overhaul my training, or chase some miracle supplement. I restored my internal terrain—and it changed what I could do on the outside. For me, this wasn’t about turning back the clock. It was about running forward with a better engine.

FROM JD:

• I received a perfusion of yFFP at the beginning of May 2025 and immediately I felt a boost of energy.

• Two months later, the symptoms of Parkinson Disease did’nt disappear but I still have a great energy the whole day. Some days the need for medication is lowered.

• Next to the boost of energy, I was very thankful for the holistic approach and the inspiring information about diet: my intestinal tract and brains are “ on top”.

• I continue the HBOT and after 3 sessions the oxygen marks already 100% !

• I can assure that the treatment with yFFP is worth it, even I had to travel from Europe!

​

FROM JD's HUSBAND:

I'd like to mention that Prof. Dr. Paul Santens, Head of Neurology Department, University Ghent and European opinion leader in Parkinson Disease, reported that : "after her treatment in the USA-Houston, he concluded after clinical investigation that patient is nearly PD symptoms free."

As husband of JD I confirm here with her and Prof. Santens' findings.

• Life seemed even better.

• Things I had looked at before seemed more interesting.

• More clarity about making decisions and the road ahead. Better able to plan and execute actions – calmly, efficiently, effectively.

• Not tired after working hard all day

• Coming up with creative solutions

• A couple days later after computer crash, a couple times while driving in mostly stopped traffic, I took it more in stride.​

​

Objective Measures About 1 Week After Infusion

Blood pressure

• Normal ~118/78

• After ~115/72 to as low as 108/65

​

Labs

• Glucose 109 to 96 at 1 wk (was 88 two days after)

• Very slight Hemoglobin A1c reduction (.1)

• Due to 1 liter blood removal hemoglobin, hematocrit decreased below reference range – consistent with removing blood donation. It steadily built back up.​

​

Oura ring reported

• High sleep and readiness scores

• More deep sleep – over 1 hr many nights

• More REM sleep – over 1 hr many nights

• Higher blood oxygen 99% - to 100% some nights.​​

The plasma infusion showed promising age reversal with a reduction in biological age and improvements in metabolic markers. However, the significant drop in blood cell counts is a potential area of concern that should be monitored closely by a healthcare professional.

​​

Around One Month

• Very good stamina

• Even better no-nonsense evaluations in business and life situations, and decision making

• Feeling very well grounded, confident and “happy”

• Around 45-60 min deep sleep most nights

• Exercise Stamina (CA elliptical machine) 12/24/2024 113 strides in 25 sec. baseline was 101 so about 12% improvement​

​

Overall, there were some positive changes in metabolic markers (glucose, insulin) and lipids, but also some areas of potential concern (sodium, MCV, RBC).

• After 10 years of struggling with my right knee, young plasma injection has been a life-changing experience for me, just like Ninja and all sports enthusiasts.

• Thanks to @dr.stan_jones, @spectrumplasma, @hanandamoves, @dian.ginsberg_md, I'm getting back to doing what I love….. Having fun with life!

​Diagnosis: Bulbar-onset ALS (diagnosed 6 months prior to presentation)

Treatment:

• Underwent 3L Young Plasma Exchange (YPE) in November 2024 per Golden Gift study protocol

• Ongoing peptide therapy, targeted supplements, and nutritional plan guided by lipid-based metabolic profiling

• Baseline and follow-up assessments: PNOE metabolic analysis, pulmonary function testing, InBody composition analysis, and grip strength

Outcomes:

• PNOE and pulmonary function remained stable, indicating no progression in respiratory decline

• Grip strength showed slight reduction, but muscle mass remained stable

• Subjective improvements:

  • Easier, more natural breathing—especially in the supine position

  • Improved gym performance and strength

  • Noticeable improvement in speech and swallowing

• Patient is scheduled for a second round of 3L YPE

What made me want to try young plasma?​

• I had stumbled upon plasma-based therapy as a highly regarded intervention, and had participated in Dr. Kiprov's TPE trials, with what seemed like limited success. With further investigation, including advice from trusted co-travellers, I discovered yFFP TPI, and decided that it appeared to be the best option currently available for systemic rejuvenation. I then spoke with the folks involved in its availability, liked their story and attitudes, and decided to go for it. I am not a rich guy, so the cost was a bit of a cold dip, but I decided that at my age (71, at the time), it was a wise use of resources. ​

What changes did I notice in energy, mood, focus or symptoms?​​

• In the days following the treatment (at the excellent Thrive Clinic, in Houston), I felt better in every way, but not so much so that I could positively attribute it to the intervention. In the days that followed I realized that some longstanding symptoms had disappeared.  For one, since pinching a nerve at C5, at least 10 years ago, I've had a patch on each arm of intense false itching, which I would sometimes unconsciously scratch until it bled. It was gone when I returned from Houston, and never returned.  Amazing, since my GP said there was nothing that could be done about it.  Secondly, I am a bit pre-diabetic, and had a symptom that I call "pebble feet", which is due to damaged nerves. Amazingly, it spontaneously disappeared after the therapy, but unfortunately returned after a few weeks - probably because I did not change my eating habits like a smarter person would have.  Finally, for at least 15 years, I have suffered shoulder pain, doubtless due to rotator cuff damage triggered by reaching too high when trimming a tree.  It even prevented me from sleeping on that side for more than a few minutes. ...And suddenly, it was gone! All was well until this genius decided to trim some trees, which retriggered it.  ​

​

Would I tell someone else who is considering it? 

• ​I am like a walking billboard for yFFP TPI, telling anybody who seems interested. I am not sure any of them have taken the plunge, but that's their problem. I think the price tag is a bit much for most people in my economic class, but there's not much that can be done about that.  I am considering a booster!      

​Chief Complaints: Chronic fatigue, low libido, multiple joint pains, cognitive sluggishness

Treatment:

• Underwent 3L YPE

• Received multiple joint injections with young Fresh Frozen Plasma (yFFP)

Outcomes:

• Reports significantly increased energy and a noticeable reversal in visible aging

• Joint pain resolved, with increased mobility and functionality

• Memory and cognitive sharpness improved

• Regained the ability to travel and keep up with her 24-year-old son, reporting a return to full activity and youthful engagement with life

My 80 year old parents did 2 liter exchanges(1 liter out-1 liter in a week apart) just over 2 months ago and my mom also had the plasma put directly into her bad knee that she was thinking about replacing and had been getting cortisone shots. 

My dad has afib and he really notices an energy improvement as well as his NT-probnp has come down from 1330 to just over 900--am looking forward to the 4 month results

my moms knee has absolutely no pain.  my mothers knee 2 months after the plasma --was hurting bad--now no pain

​she really notices an improvement in my dad--much stronger she said

the other day they played 18 holes of golf after a bad rain and the rule was 'cart path only ' so you could not bring the cart to the ball

​you had to park and carry your clubs to the ball--so he must have walked 5 miles--felt great

​she said she sees it around the house when he is working--he has way more strength and general stamina

​her words were 'The plasma is working'.

• My and my mom’s infusions went well on Sunday.  We’ve each had a total of 1800mls over 3 infusions in two weeks.

• In my mom’s recent visit compared to two weeks ago I found my mom is moving better, with more confidence and more stability, less looking down and less wobbly.  She seems to struggle less with finding her words and forming cohesive sentences.  She seems less irritable. 

• She and my dad report her feeling better, doing better, moving better, improving.

• I’ve been off anti-inflammatories since my first infusion, seen improvement in my hip mobility (I’ve had a torn labrum for a year or so.) I’ve been able to workout more often and more vigorously.

• My eyesight is definitely clearer: I can see my clock at night without my glasses, and I can read smaller text with ease.  I did a micro-needling yFFP facial and my skin looks fantastic. I’m looking for evidence of regrowth in my hairline😉 

Spoke with a Parkinson’s patient today, age 53.

She had 2L of yFFP infused in early march, so she's 3 months out. 

 

At the time, she decided to only do 2L, because she wasn't sure it would work and because it was expensive. 

​

Her symptoms included (at the time of treatment):

• significant rapid tremor in her right quadriceps that was causing pain and interrupting sleep - this was the most recent, and most troublesome symptom she had.

• right hand tremor that was interfering with typing and daily activities

• a "cluster of minor symptoms"

 

As of today, the tremor in her right leg is entirely gone, no longer causing pain, shaking, or keeping her awake. 

​

Her right hand tremor is still present, but the fluidity of use of her hand is better, and she is able to easily type again, so it's not causing problems like it was before

​

The cluster of minor symptoms doesn't seem to be significantly different. 

• Called me three days after infusion (also had hyperbaric oxygen, red light therapy, healthy meals )

• Was extremely pleased with the physicians, clinic and people – physicians took time and offered much advice. He felt safe.

• After traveling and not slept well on an uncomfortable hotel bed – can’t say he feels better at that time.

• Had recent hip replacement surgery

• No improvement in exercise bike and swimming
  performance. He says it could be because of the hip replacement

• Lower pulse rate, especially when sleeping from 44 to 40

• Blood sugar monitor and it shows an average of about 10 points lower overall

​

“My leg, specifically my calf has been swollen 2 to 3 times normal size from the surgery and suddenly in the last couple days it's reduced dramatically.

Because of the surgery, I gained 12 pounds and in spite of eating low carbs and higher protein, my weight would not bulge but suddenly in the last three days I'm losing weight like I normally would from that diet.

Two different people have said to me'you must be doing something different. Your skin is glowing and looks really great.'"

​

One Month After

• Liver enzymes, which are usually slightly elevated dramatically improved Ast-21, Alt-15

• LDL 147 normally I'm 220

• My total cholesterol dropped 60 points.

• My HDL (good cholesterol) went up eight points and my other cholesterol number like small density improved to safe levels.

• I can't say I feel any different but my blood test show a much healthier status. I will test again in a couple months to see how long they last.

• I received 3 L of young plasma. It was done over three days and starting with the second day when I exerted myself, I had shortness of breath. this lasted for two days afterwards, but by the third day, after receiving the 3 L I could swim laps again.

• My wife had the same 3 L of plasma and neither one of us felt normal for three or four days. I also had loose stool for five days.

• Logically we know it’s good for us and my biggest benefit are in my blood  test results as six months later my cholesterol has remained at 136 for LDL when it previously was 220. Also, for both my wife and myself, our liver enzymes improved dramatically to the lower half of the range.​

• My wife’s cholesterol was not affected. 

• On 2/11 I had a liter of young plasma injected.  The protocol was to remove two liters of blood and inject one liter of young plasma, less expensive and less involved than using apheresis.  We couldn't get the large needle working for removal of the blood, so I just received the one liter injection (smaller needle).

• I had driven from CA for the procedure and was expecting to be somewhat tired, but on the drive back I had plenty of energy.  It just seemed like a normal day.  I fact, I was highly motivated to do exercise 'snacks' (a sprint and some pushups) whenever I stopped for gas.  I continued to experience more energy for some time, and it doesn't feel like I have returned to the old baseline four months later.  I also have some immune system issues that have gotten easier.

• I definitely recommend young plasma, although next time I will get at least two liters.

• (Dr) Julie was very good to deal with. . . Nice lady . . .

• . . . my particular issue . . . developed high blood pressure fairly recently due to what I believe is a dysregulated cGMP

  pathway.

• Prior . . . blood pressure high of about 154/90 , an average of 140/84 and be in my target range of below 135/85 7% of the time.

• After the transfusion (infusion) my blood pressure corrected within two days (I didn’t measure it for two days so may have been sooner).

• Now its in my target range of below 135/85 100% of the time. Average around 125/73

"Based on my readings at home I would say my systolic dropped about 15 points and diastolic about 11 points, probably even a bit more.

​​As well during this dysregulation I had a difficult time doing any cardio, also had constant low grade headaches and eye pressure.

​​I seem good now in all respects.

I am satisfied for sure."​

Several of our patients are reporting better mental clarity, faster healing, and an overall sense of vitality that feels like turning back the clock.

What we hear most is an almost immediate improvement in energy and focus, and within a few sessions better sleep and less brain fog.

It’s been one of the most promising regenerative tools we’ve introduced.

​

Thrive Medicine Team

• I injected my knee with  Young Plasma (about 10 ccs) and also injected myself IM with whatever was left (30 ccs). I am pleased to tell you my knee pain is completely gone and my double vision is also gone. Since my double vision is secondary to ophthalmic Graves, it stands to reason to say that  Young Plasma cures autoimmune diseases.

​Medical History: Poorly controlled Type 2 Diabetes, hypertension, hyperlipidemia, coronary artery disease (status post-CABG), cognitive decline, unsteady gait

​

Treatment:

3L YPE protocol

Outcomes:

• Reported notable increases in energy, stamina, and mental clarity

• Diabetes has become better controlled, with reduction in blood glucose and improvement in insulin sensitivity

• Positive body composition changes: weight loss primarily from fat, with muscle gain observed on follow-up InBody scan

• Hey there, i am emailing you in regards to how my mothers injections went. I did four IM injections 10cc each, one on each shoulder and hips, within the next two days she did voiced that she felt better, such as walking - long distances weren't hurting her hips and she was also able to put on her bra without help, which she has a hard time achieving due to her RA dx. She was very happy with how the plasma affected her in a positive manor. 

• Positive subjective report – mentally sharp

• No side effects

• Neuropathy improved - Pre diabetes symptom uncomfortable “hot” feet – disappeared 1 week after

• When walking had felt like “walking on pebbles (well known symptom) – completely gone 1 wk after

• Stand on one leg 20 sec up to avg 40 sec

• ​Chronic high triglycerides - from out of reference range to in range​​

​

“It’s remarkable it could go away so fast.”​

“...for the money the results are much better than anticipated compared to going to clinics”

• I had a 79 y/o male with BPH, negative grail test (to confirm not prostate ca), who was getting up multiple times a night to urinate.  I injected approximately 5 cc YFFP into his prostate.  He now reports only getting up twice a night.  I thought this was a big win.  Improved quality of sleep = improved quality of life!  YAY!

• My wife really didn’t have a lot wrong with her health wise. But she does has some sort of nerve problem in her feet, when they get cold she said they would hurt a bit, she says they now no longer hurt when they get cold.​​​

• She also got a mood enhancement, and the plasma facial seems to have maybe soften her face, but I am not sure.

• Already in excellent health, travels to many locations for innovative therapies – gene therapy, stem cells and others

• After two week adjustment saw a subjective increase in mood and energy levels, gradually returned to normal over several weeks.

• May have seen increase in libido, lasted for several weeks​

• Travels to many locations for innovative therapies

• Achilles heel: hormone balance

• One year later reported still having positive effects

• Has known histamine sensitivity. Had histamine rich long, slow-cooked meat lunch after. Headache after, unable to determine how much was a result of the meal or plasma.